Download the Nanodrop 1000 software from Thermo Fisher - https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/molecular-spectroscopy/ultraviolet-visible-visible-spectrophotometry-uv-vis-vis/uv-vis-vis-instruments/nanodrop-microvolume-spectrophotometers/nanodrop-software-download.html

Extract the zipped file to an easily accessible folder (Desktop or Documents).  

From the unpacked folder "ND1000_3.8.1" run the following setup files - Need to use a compress/decompression tool like 7Zip for this. 

1) ND1000/LVRuntime7/lvruntimeeng71.msi
2) ND1000/NI-VISA 4.4.1/setup.exe
3) ND1000/NanoDrop 1000 V3.8.1.msi
4) 64bitdriver/NanoDrip 1000 64bit Driver.msi

5) Now copy and paste the following text into a file called bosdescriptor.reg
; This file is needed to install NanoDrop 1000 under Windows 10
Windows Registry Editor Version 5.00

[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\usbflags\245710020002]
"SkipBOSDescriptorQuery"=dword:00000001
; End of file

Working example of bosdescriptor.reg file 


6) add the created .reg file to the windows registry by double clicking it
7) Plug in the device


Referenced link - https://www.researchgate.net/post/I_have_successfully_installed_the_ThermoFisher_NanoDrop_1000_under_Windows_10_64bit

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