Before you go on...
Much of this article assumes an understanding of the workings of and the differences between Profiles, Roles, and Programs in Fluxx.
For background materials to understand these differences, please see our Roles, Program, and Profiles (or Portals) Definitions Page.
Additionally, Fluxx has two great articles discussing many of the things found in this article. This article deals with explaining Profiles, Roles, and Permissions explicitly.
A second article discusses Editing Profile Permissions, which should be a key takeaway from this page.
Profiles Tab
Screenshot below